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Chemistry

Working Paper

Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Cofactors

Nathaniel Goldberg, Anders M. Knight, Ruijie Zhang, Frances H. Arnold

Version 1 posted 05 November 2019

1,231

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Chemistry

Working Paper

Directed Evolution of an Feᴵᴵ-Dependent Halogenase for Asymmetric C(sp³)-H Chlorination

Sabine Duewel, Luca Schmermund, Tabea Faber, Klaus Harms, Vasundara Srinivasan, Eric Meggers, Sabrina Hoebenreich

Version 1 posted 05 November 2019

979

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Chemistry

Working Paper

Development of 96 Multiple Injection-GC-MS Technique and Its Application in Protein Engineering of Natural and Non-Natural Enzymatic Reactions

Anja Knorrscheidt, Pascal Püllmann, Eugen Schell, Dominik Homann, Erik Freier, Martin Weissenborn

Version 1 posted 03 December 2019

1,025

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1

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Chemistry

Working Paper

A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons

Xiongyi Huang, Marc Garcia-Borràs, Kun Miao, S. B. Jennifer Kan, Arjun Zutshi, K. N. Houk, Frances H. Arnold

Version 1 posted 26 September 2018

1,442

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Chemistry

Working Paper

Directed Evolution of Flavin-Dependent Halogenases for Atroposelective Halogenation of 3-Aryl-4(3H)-quinazolinones via Kinetic or Dynamic Kinetic Resolution

Harrison M. Snodgrass, Dibyendu Mondal, Jared Lewis

Version 1 posted 26 April 2022

612

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Chemistry

Working Paper

Directed evolution of a bright variant of mCherry: Suppression of non-radiative decay by fluorescence lifetime selections

Srijit Mukherjee, Premashis Manna, Sheng-Ting Hung, Felix Vietmeyer, Pia Friis, Amy Palmer, Ralph Jimenez

Version 1 posted 16 March 2022

1,740

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1

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Chemistry

Working Paper

Directed Evolution of an Artificial Hydroxylase Based on a Thermostable Human Carbonic Anhydrase Protein

Iori Morita, Adriana Faraone, Kailin Zhang, Roman P. Jakob, Timm Maier, Thomas R. Ward

Version 1 posted 26 April 2024

428

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Chemistry

Working Paper

Directed Evolution of a Modular Polyketide Synthase Thioesterase for Generation of a Hybrid Macrocyclic Ring System

Maria L. Adrover-Castellano, Brian J. Curtis, Jennifer J. Schmidt, Carolyn A. Glasser, Damilola E. Olukorede, Fengrui Qu, David H. Sherman

Version 2 posted 11 September 2024

1,016

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Chemistry

Working Paper

Directed Evolution Enables Dynamic Control of Transient Intermediates for Anti-Markovnikov Wacker-Tsuji-Type Oxidation of Unactivated Alkenes

Cindy Klaus, Jordi Soler, Grzegorz Kubik, Yosephine Gumulya, Yue Hui, Ella J. Watkins-Dulaney, Max-Luca Heitland, Marc Sommer, Alina Klein, Julia L. Kowal, Hartmut H. Niemann, Frances H. Arnold, Marc Garcia-Borràs, Stephan C. Hammer

Version 2 posted 17 September 2024

982

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Chemistry

Working Paper

Directed Evolution of Protoglobin Optimizes the Enzyme Electric Field

Shobhit S. Chaturvedi, Santiago Vargas, Pujan Ajmera, Anastassia N. Alexandrova

Version 1 posted 28 February 2024

1,073

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50 results in Directed Evolution in Keywords: Directed Evolution

Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Cofactors

Directed Evolution of an Feᴵᴵ-Dependent Halogenase for Asymmetric C(sp³)-H Chlorination

Development of 96 Multiple Injection-GC-MS Technique and Its Application in Protein Engineering of Natural and Non-Natural Enzymatic Reactions

A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons

Directed Evolution of Flavin-Dependent Halogenases for Atroposelective Halogenation of 3-Aryl-4(3H)-quinazolinones via Kinetic or Dynamic Kinetic Resolution

Directed evolution of a bright variant of mCherry: Suppression of non-radiative decay by fluorescence lifetime selections

Directed Evolution of an Artificial Hydroxylase Based on a Thermostable Human Carbonic Anhydrase Protein

Directed Evolution of a Modular Polyketide Synthase Thioesterase for Generation of a Hybrid Macrocyclic Ring System

Directed Evolution Enables Dynamic Control of Transient Intermediates for Anti-Markovnikov Wacker-Tsuji-Type Oxidation of Unactivated Alkenes

Directed Evolution of Protoglobin Optimizes the Enzyme Electric Field

50 results in Keywords: Directed Evolution