Hypercoagulability linked to pregnancy in a group of Colombian patients, observational study of binding clinical and laboratory alterations.

Introduction: The present study sought to study thrombophilias associated with venous thromboembolism during pregnancy. Methods: The present study is of a descriptive observational type in which the clinical and laboratory alterations were analyzed in a cohort of Latin American pregnant women with the denominator of thrombotic events during pregnancy. Results: The mean age was 24.5+7.6 years, of which 9 patients (10.3%) had a history of thromboembolism , 23 patients (26.4%) had had at least one fetal loss. Elevated Antiphosphatidylserine antibodies were found in 23 patients (26.4%), elevated antibodies against Beta2-Glycoprotein in 20 patients (22.9%), positive lupus anticoagulant in 16 patients (18.3%), elevated Factor VIII in 13 patients (14.94%), Elevated Factor IX in 15 patients (17.2%), Elevated Factor XI in 12 patients (13.7%), Prothrombin Mutation in 7 patients (8.07%). Conclusions: The results found here indicate the high prevalence rate of thrombophilic alterations. underdiagnosed in pregnant women.