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Neuroimmune-Mediated Mood/Psychotic Syndromes: A case Series (n=45) Treated with Immunotherapy

07 November 2024, Version 1
Video
Depression
This content is an early or alternative research output and has not been peer-reviewed by Cambridge University Press at the time of posting.
This item is a response to a research question in Depression
Q. Is immune activation simply a non-specific marker of depression severity or chronicity or does it indicate an underlying pathophysiological path to depressive or other mood disorders?
Explore Is immune activation simply a non-specific marker of depression severity or chronicity or does it indicate an underlying pathophysiological path to depressive or other mood disorders? in full on Cambridge Core
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Abstract

Associate Professor Elizabeth Scott discusses the complexities in diagnosing and treating neuroimmune-mediated mood and psychotic syndromes, emphasising the importance of moving beyond traditional diagnostic categories within neurology, psychiatry, and paediatrics. This case series highlights the potential of immunotherapies for young individuals experiencing complex, treatment-resistant syndromes and advocates for early intervention. Future research is needed to establish standardised screening protocols, develop targeted immunotherapies, and investigate underlying neurophysiological pathways. Such advancements aim to improve early detection and treatment, potentially reducing the severe impact on the lives of affected individuals.

Keywords

Neurommune-mediated mood syndromes
Depression

Video

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Title
Neuroimmune-Mediated Mood/Psychotic Syndromes: Case Series Treated with Immunotherapy - A.Prof Scott
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A YouTube link to the lecture.
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Version History

Nov 07, 2024 Version 1

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The content is available under CC BY 4.0 [opens in a new tab]

DOI

10.33774/coe-2024-rm4z9
D O I: 10.33774/coe-2024-rm4z9 [opens in a new tab]

Author’s competing interest statement

A/Prof Elizabeth Scott is Principal Research Fellow at the Brain and Mind Centre, The University of Sydney. She is Discipline Leader of Adult Mental Health, School of Medicine, University of Notre Dame, and a Consultant Psychiatrist. She was the Medical Director, Young Adult Mental Health Unit, St Vincent’s Hospital Darlinghurst until January 2021. She has received honoraria for educational seminars related to the clinical management of depressive disorders supported by Servier, Janssen and Eli-Lilly pharmaceuticals. She has participated in a national advisory board for the antidepressant compound Pristiq, manufactured by Pfizer. She was the National Coordinator of an antidepressant trial sponsored by Servier.

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

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